Physics of Cellular Systems

   Publications

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28. Tube geometry controls protein cluster conformation and stability on the endoplasmic reticulum surface. Liam T. Kischuck and Aidan I. Brown. Soft Matter. 19: 6771 - 6783 (2023)
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27. Quantitative modeling of EGF receptor ligand discrimination via internalization proofreading. Jaleesa A. Leblanc, Michael G. Sugiyama, Costin N Antonescu, and Aidan I. Brown. Physical Biology. 20: 056008 (2023)
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26. Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling. Michael G. Sugiyama, Aidan I. Brown, Jesus Vega-Lugo, Andrew M. Scott, Khuloud Jaqaman, Gregory D. Fairn, and Costin N Antonescu. Nature Communications. 14: 2681 (2023)
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25. Mitochondrial mRNA localization is governed by translation kinetics and spatial transport. Ximena G. Arceo, Elena F. Koslover, Brian M. Zid, and Aidan I. Brown. PLOS Computational Biology. 18: e1010413 (2022)
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24. Diffusive search and trajectories on spatial networks: a propagator approach. Zubenelgenubi C. Scott, Aidan I. Brown, Saurabh S. Mogre, Laura M. Westrate, and Elena F. Koslover. European Physical Journal E. 44: 80 (2021)
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23. Design principles for the glycoprotein quality control pathway. Aidan I. Brown, and Elena F. Koslover. PLoS Computational Biology. 17: e1008654 (2021)
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22. Getting around the cell: physical transport in the intracellular world. Saurabh S. Mogre, Aidan I. Brown, and Elena F. Koslover. Physical Biology 17: 061003 (2020)
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21. Impact of global structure on diffusive exploration of organelle networks. Aidan I. Brown, Laura M. Westrate, and Elena F. Koslover. Scientific Reports. 10: 4984 (2020)
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20. Mitochondrial Fission and fusion dynamics generate efficient, robust, and evenly distributed network topologies in budding yeast cells. Matheus P. Viana, Aidan I. Brown, Irina A. Mueller, Claire Goul, Elena F. Koslover, and Susanne M. Rafelski. Cell Systems. 10: 287-297 (2020)
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19. Theory of nonequilibrium free energy transduction by molecular machines. Aidan I. Brown and David A. Sivak. Chemical Reviews. 120: 434-459 (2020)
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18. Drive, filter, and stick: A protein sorting conspiracy in photoreceptors. Aidan I. Brown and Elena F. Koslover. Journal of Cell Biology (Spotlight article). 218: 3533-3534 (2019). ***Not peer reviewed***
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17. High-resolution and high-accuracy topographic and transcriptional maps of the nucleosome barrier. Zhijie Chen, Ronen Gabizon, Aidan I. Brown, Antony Lee, Aixin Song, Cesar Diaz Celis, Elena F. Koslover, Tingting Yao, and Carlos Bustamante. eLife. 8: e48281 (2019). Featured in eLife Insight.
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16. Breaking time-reversal symmetry for ratchet models of molecular machines. Arshia Zarrin, David A. Sivak, Aidan I. Brown. Physical Review E, 99: 062127 (2019)
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15. Pulling cargo increases the precision of molecular motor progress. Aidan I. Brown and David A. Sivak. Europhysics Letters, 126: 40004 (2019)
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14. Allocating and splitting free energy to maximize molecular machine flux. Aidan I. Brown and David A. Sivak. Journal of Physical Chemistry B, 122: 1387-1393 (2018)
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13. Allocating dissipation across a molecular machine cycle to maximize flux. Aidan I. Brown and David A. Sivak. Proceedings of the National Academy of Sciences of the USA, 114: 11057-11062 (2017)
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12. Toward the design principles of molecular machines. Aidan I. Brown and David A. Sivak. Physics in Canada, 73: 61-66 (2017)
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11. A model of autophagy size selectivity by receptor clustering on peroxisomes. Aidan I. Brown and Andrew D. Rutenberg. Frontiers in Physics, 5: 14 (2017)
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10. Effective dissipation: breaking time-reversal symmetry in driven microscopic energy transmission. Aidan I. Brown and David A. Sivak. Physical Review E, 94: 032137 (2016)
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9. Uniform spatial distribution of collagen fibril radii within tendon implies local activation of pC-collagen at individual fibrils. Laurent Kreplak, Aidan I. Brown, and Andrew D. Rutenberg. Physical Biology, 13: 046008 (2016)
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8. Single file diffusion into a semi-infinite tube. Spencer G. Farrell, Aidan I. Brown, and Andrew D. Rutenberg. Physical Biology, 12: 064001 (2015)
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7. Cluster coarsening on drops exhibits strong and sudden size-selectivity. Aidan I. Brown and Andrew D. Rutenberg. Soft Matter, 11: 3786-3793 (2015)
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6. An equilibrium double-twist model for the radial structure of collagen fibrils. Aidan I. Brown, Laurent Kreplak, and Andrew D. Rutenberg. Soft Matter, 11: 8500-8511 (2014)
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5. Protein translocation without specific quality control in a computational model of the Tat system. Chitra R. Nayak, Aidan I. Brown, and Andrew D. Rutenberg. Physical Biology, 11: 056005 (2014)
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4. PEX5 and ubiquitin dynamics on mammalian peroxisome membranes. Aidan I. Brown, Peter K. Kim, and Andrew D. Rutenberg. PLoS Computational Biology, 10: e1003426 (2014)
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3. A storage-based model of heterocyst commitment and patterning in cyanobacteria. Aidan I. Brown and Andrew D. Rutenberg. Physical Biology, 11: 016001 (2014)
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2. Heterocyst placement strategies to maximize the growth of cyanobacterial filaments. Aidan I. Brown and Andrew D. Rutenberg. Physical Biology, 9: 046002 (2012)
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1. Reconciling cyanobacterial fixed-nitrogen distribution and transport experiments with quantitative modelling. Aidan I. Brown and Andrew D. Rutenberg. Physical Biology, 9: 016007 (2012)
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